Toure, Cheikh Talibouya and Dieng, Idrissa and Sankhe, Safietou and Kane, Mouhamed and Dia, Moussa and Mhamadi, Moufid and Ndiaye, Mignane and Faye, Ousmane and Sall, Amadou Alpha and Diagne, Moussa Moise and Faye, Oumar (2024) Genomic Characterization of a Bataï Orthobunyavirus, Previously Classified as Ilesha Virus, from Field-Caught Mosquitoes in Senegal, Bandia 1969. Viruses, 16 (2). p. 261. ISSN 1999-4915
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Abstract
Bataï virus (BATV), belonging to the Orthobunyavirus genus, is an emerging mosquito-borne virus with documented cases in Asia, Europe, and Africa. It causes various symptoms in humans and ruminants. Another related virus is Ilesha virus (ILEV), which causes a range of diseases in humans and is mainly found in African countries. This study aimed to genetically identify and characterize a BATV strain previously misclassified as ILEV in Senegal. The strain was reactivated and subjected to whole genome sequencing using an Illumina-based approach. Genetic analyses and phylogeny were performed to assess the evolutionary relationships. Genomic analyses revealed a close similarity between the Senegal strain and the BATV strains UgMP-6830 from Uganda. The genetic distances indicated high homology. Phylogenetic analysis confirmed the Senegal strain’s clustering with BATV. This study corrects the misclassification, confirming the presence of BATV in West Africa. This research represents the first evidence of BATV circulation in West Africa, underscoring the importance of genomic approaches in virus classification. Retrospective sequencing is crucial for reevaluating strains and identifying potential public health threats among neglected viruses.
Item Type: | Article |
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Subjects: | GO for STM > Multidisciplinary |
Depositing User: | Unnamed user with email support@goforstm.com |
Date Deposited: | 07 Feb 2024 05:32 |
Last Modified: | 07 Feb 2024 05:32 |
URI: | http://archive.article4submit.com/id/eprint/2658 |