Lipid Peroxidation and Antioxidant Effects of Lead Acetate: An Experiment in Various Organs of Oreochromis mossambicus (Peters 1852)

The industrial wastes are extremely deadliest agents which are heavily settle into the aquatic ecosystems as the results they rising uncountable health defects towards aquatic species. In the present study, the effect of heavy metal Lead acetate (Pb(C2H3O2)2) exposure towards fingerlings of Oreochromis mossambicus. The fish were exposed to sub lethal concentration LC50 of Pb(C2H3O2)2 for 96 hrs. for 21 and 28 days and the various organs viz. liver, gill, kidney and muscle tissues were studied for lipid peroxidation (LPO), Reduced glutathione (GSH), glutathione peroxidase (GPx), Catalase (CAT), and superoxide dismutase (SOD). These observed mean data were subjected to student ‘T’ test. The Pb(C2H3O2)2 exposed to O. mossambicus fingerlings which tested on various organs of liver, gill, kidney and muscle for assessing the effect of LPO, GSH, GPx, CAT and SOD on control and treated fish. The predominant effects were observed at 28 days of exposer period, the liver, gill, kidney and muscle has drastically suffered by exposer of Pb(C2H3O2)2. Liver: 2.89, 2.40, 1.21, 1.33 and 0.42μmole/mg of protein/hr, Gill: 0.948, 1.18, 0.326, 0.62 and 0.24μmole/mg of protein/hr, Kidney: 0.968, 1.56, 1.006, 0.46 and 0.26 μmole/mg of protein/hr and Muscle: 0.988, 1.12, 0.226, 0.62 and0.12 μmole/mg of protein/hr were recorded on tissue of treated fish. Moreover, the respective concentration of Pb(C2H3O2)2 exposed against fingerlings which compared with control and experimental group, the percentage of concentration on LPO, GSH, GPx, CAT and SOD of various organs of treated fish were increased as well as decreased in the experimental group then the control group. The huge exposure of Pb(C2H3O2)2 on O. mossambicus fingerlings which showed unpredictable negative health defects on various system. Beyond the threshold level of Pb(C2H3O2)2 it may interfere the various metabolic activity of organism including lipid peroxidation and antioxidant level. Hence, the present experiment which gives the great knowledge about effects of Pb(C2H3O2)2 on aquatic organism as well as health defects on faunal communities by using of higher concentration.