Heterogeneity in Metabolic Responses to Dietary Fructose

Hou, Ruixue and Panda, Chinmayee and Voruganti, V. Saroja (2019) Heterogeneity in Metabolic Responses to Dietary Fructose. Frontiers in Genetics, 10. ISSN 1664-8021

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Abstract

Consumption of fructose has dramatically increased in past few decades in children and adults. Increasing evidence indicates that added sugars (particularly fructose) have adverse effects on metabolism and lead to numerous cardiometabolic diseases. Although both fructose and glucose are components of sucrose and high fructose corn syrup, the sugars have different metabolic fates in the human body and the effects of fructose on health are thought to be more adverse than glucose. Studies have also shown that the metabolic effects of fructose differ between individuals based on their genetic background, as individuals with specific SNPs and risk alleles seem to be more susceptible to the adverse metabolic effects of fructose. The current review discusses the metabolic effects of fructose on key complex diseases and discusses the heterogeneity in metabolic responses to dietary fructose in humans.

Item Type: Article
Subjects: GO for STM > Medical Science
Depositing User: Unnamed user with email support@goforstm.com
Date Deposited: 04 Feb 2023 09:47
Last Modified: 23 Dec 2023 05:21
URI: http://archive.article4submit.com/id/eprint/207

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