ANALYSIS OF ANTIFUNGAL ACTIVITY USING POWDERED CUTTLEBONE Sepia pharaonis EHRENBERG, 1831 AGAINST SELECTED PATHOGENS

Sea food is regarded as a good source of animal protein since it had a high content of polyunsaturated fatty acids. Cephalopods are considerably important a food resource as well as in scientific investigations. The aim of the present study is to evaluate the antifungal activity of methanolic extract of powdered cuttlebone of Sepia pharaonis against five fungal strains such as, Candida albicans, Aspergillus flavus, Mucor, Aspergillus niger and Aspergillus fumigates using well diffusion method. The methanolic extract was active against Candida albicans, Mucor and Aspergillus fumigates at higher concentarion level and dormant against Aspergillus flavus and Aspergillus niger. These results revealed that the methanolic extract of powdered cuttle bone possess relatively good antifungal activity.