Chronic Granulomatous Disease: A Recent Approach

Sahoo, Manas Ranjan (2023) Chronic Granulomatous Disease: A Recent Approach. In: Novel Research Aspects in Medicine and Medical Science Vol. 4. B P International, pp. 92-98. ISBN 978-81-19761-20-3

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Abstract

Chronic granulomatous disease (CGD) is a fatal inborn error of immunity due to defective respiratory burst in phagocytes resulting in recurrent bacterial and fungal infection. It has to be suspected when in early infancy children presents with recurrent bacterial,fungal infection in the form of pneumonia,deep seated abscess.In Indian setting in tubercular infections presenting as persistent pneumonia CGD has to be considered.It is screened by Dihydro rhodamine assay and confirmed by molecular genetic testing.Prophylactic antibiotics, antifungal administration, aggressive management of infections and its complicationare key for longterm survival.Hematopoetic stem cell transplantation (HSCT) remains only curative treatment at present and future lies in gene therapy.

Item Type: Book Section
Subjects: GO for STM > Medical Science
Depositing User: Unnamed user with email support@goforstm.com
Date Deposited: 04 Oct 2023 05:36
Last Modified: 04 Oct 2023 05:36
URI: http://archive.article4submit.com/id/eprint/1624

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