Abbasi, Ata and Phelps, David S. and Ravi, Radhika and Floros, Joanna (2021) Can Prophylactic High Flow of Humidified and Warmed Filtered Air Improve Survival from Bacterial Pneumonia and SARS-CoV-2 in Elderly Individuals? The Role of Surfactant Protein A. Antioxidants, 10 (5). p. 640. ISSN 2076-3921
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Abstract
In this opinion article, we discuss a serendipitous observation we made in a study investigating survival in aged mice after bacterial infection. This observation involved a non-invasive ventilation approach that led to variable and higher survival in male and female mice with different genetic backgrounds for the innate immune molecule, surfactant protein A (SP-A). We suggest that employing the best ventilatory modality, whether that be HFNC or another method, may augment the role of other factors such as SP-A genetics and sex in a personalized approach, and may ultimately improve the outcome.
Item Type: | Article |
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Subjects: | GO for STM > Agricultural and Food Science |
Depositing User: | Unnamed user with email support@goforstm.com |
Date Deposited: | 04 Oct 2023 04:13 |
Last Modified: | 04 Oct 2023 04:13 |
URI: | http://archive.article4submit.com/id/eprint/1349 |