Flupirtine: An Exigency Call for Medication Vigilant

The purpose of this monograph is to provide an extensive review of the drug Flupirtine clinical
applications and its safety-related issues. While existing Non- Steroidal Anti-inflammatory Drugs
(NSAIDs) and Opioids which are used in the treatment of pain had some common adverse effects this
drug is devoid of adverse effects exhibited by NSAIDs and Opioids and is routinely used in clinics as
an analgesic particularly in India. Apart from its routine clinical use recently there are growing
concerns related to this drug for its hepatotoxicity hence it is withdrawn from the market of European
unions. Therefore, this monograph helps you to analyze its chemical nature, applications, recent
issues related to hepatotoxicity events that are reported with evidences in both the literature and also
databases. So that readers can gain awareness concerning this drug and also this can pose a
challenge to the regulatory bodies in India whether this drug can be safer to continue in the market or
any still further data can be required to prove its safety and efficacy because of increasing concerns
related to hepatotoxic events in recent days.